Embodiments of the present systems and methods may detect cognitive decline using changes in activities of daily living. For example, in an embodiment, a computer-implemented method for determining effects of cognitive loading on a person may comprise receiving data from at least one physical movement sensor attached to a person, the data recorded while the person is repeatedly performing a physical task and while the person is under cognitive loading during at least some of the performances of the task, determining physical movements of the person in response to the cognitive loading from the received data for each of the performances of the task, and determining an effect of cognitive loading based on the physical movements of the person while performing the physical task without cognitive loading and while performing the physical task with cognitive loading.