DEJONGE, Boudewijn, Lodewijk Maria,DURAND-REVILLE, Thomas, Francois,VERHEIJEN, Jeroen, Cunera,TOMMASI, Ruben,MUELLER, John
申请号:
PH12017500852
公开号:
PH12017500852A1
申请日:
2017.05.08
申请国别(地区):
PH
年份:
2017
代理人:
摘要:
The present invention is directed to combinations of a B-lactamase inhibitor with sulbactam and, optionally, imipenem/cilastatin. The combinations are useful for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant pathogens. More particularly, the invention relates to a combination of B-lactamase inhibitor compound 1 : or a pharmaceutically acceptable salt thereof, with sulbactam, or a pharmaceutically acceptable salt thereof, and, optionally, imipenem/cilastatin, or a pharmaceutically acceptable salt thereof.