UTILISATION DE MODIFICATEURS D'HISTONE POUR REPROGRAMMER DES LYMPHOCYTES T EFFECTEURS

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专利权人:

BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM

发明人:

YEE, CASSIAN,WANG, JUNMEI

申请号：

CA3094375

公开号：

CA3094375A1

申请日:

2019.03.28

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure provides methods for re-programming effector T cells to a central memory phenotype comprising culturing the effector T cells with a histone deacetylase inhibitor (HDACi) and IL-21. Further provided are methods of treating cancer comprising administering the central memory T cells.

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中国工程科技知识中心

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