Use of histone modifiers to reprogram effector T cells

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专利权人:

Board of Regents; The University of Texas System

发明人:

YEE, Cassian,WANG, Junmei

申请号：

AU2019243578

公开号：

AU2019243578A1

申请日:

2019.03.28

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present disclosure provides methods for re-programming effector T cells to a central memory phenotype comprising culturing the effector T cells with a histone deacetylase inhibitor (HDACi) and IL-21. Further provided are methods of treating cancer comprising administering the central memory T cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/