Enteral tubes, tube tip detection systems, and methods for detecting tube misplacement are provided. For example, a tube tip detection system comprises an enteral tube having a tip and a first light disposed at the tip that is illuminated as the enteral tube is inserted into a patient to indicate to a user of the system whether the tip is misplaced in the patient's airway. Similarly, enteral tubes are provided that comprise a tip, a length, and a light that is continuously illuminated as the enteral tube is inserted into a patient. Methods for detecting a tube misplacement in a patient's airway include embedding a light into an enteral tube, inserting the enteral tube into the patient through the patient's nose or mouth, and monitoring a location of the light as the enteral tube is inserted into the patient to determine if the tube is traveling into the patient's airway.
