PROBLEM TO BE SOLVED: To provide an agent that can dissolve dental plaque or calculus in a short period of time and does not irritate or damage tissues in oral cavity such as periodontal soft tissues or dental tissues.SOLUTION: This invention relates to an antiplaque oral composition, such as a toothpaste, gel dentifrice, tooth powder, mouth-rinse or mouthwash, tooth hardener, anti-calculus composition, gum or lozenge, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM).SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】短期間で歯垢または結石を溶かすことができ、歯根膜の軟組織または歯組織などの口腔中の組織を刺激したり溶かしたりすることのない薬剤の提供。【解決手段】キレート剤(EDTAおよびその塩)と輸送促進剤(メチルスルホニルメタン;MSM)を含む、練り歯磨き、ゲル歯磨剤、歯磨き粉、口内洗浄液またはうがい薬、歯硬化剤、歯石形成防止用組成物、ガムまたはロゼンジといった、歯垢形成防止用の経口の組成物。【選択図】なし