SOKOLOV, Evgeniy L'vovich,CHECHIK, Andrey Anatol'evich,ELOKHOVSKIY, Vladimir Yur'evich
申请号:
ES13751962
公开号:
ES2637417T3
申请日:
2013.02.22
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Method of measuring a blood glucose concentration in a human being, the method comprising: using separate electrodes fixed to a region of a human organism to successively measure high frequency impedance and low frequency impedance values of the region at intervals of predetermined time; use a measured value of high frequency impedance to determine an estimate of a tissue fluid volume in the region between the electrodes; use a measured value of the low frequency impedance to determine an estimate of a volume of an extracellular fluid in the tissue in the region between the electrodes; determine an increase in a metabolic component of the extracellular fluid volume by: determining an increase in the estimation of the fluid volume with respect to a previously measured value of the fluid volume; determination of an increase in the estimate of the volume of extracellular fluid with respect to a previously measured value of the volume of extracellular fluid; determination of a difference between the increase in fluid volume estimation and the increase in extracellular fluid volume estimation; determine an increase in blood glucose concentration by normalizing the increase in the metabolic component of extracellular fluid volume; and determine the concentration of blood glucose by adding the increase in blood glucose concentration and a previously determined concentration of blood; wherein the determination of a blood glucose concentration in a first time interval comprises adding an increase in the concentration in the first time interval and an initial blood glucose concentration.Método de medición de una concentración de glucosa en sangre en un ser humano, comprendiendo el método: usar electrodos separados fijados a una región de un organismo humano para medir sucesivamente valores de impedancia de alta frecuencia e impedancia de baja frecuencia de la región a intervalos de tiempo predeterminados; usar un valor medido de la impedancia de alta frecuencia para determina