Katherine N. Radwanski,Lan T. Nguyen,Kyungyoon Min,Cheryl Heber
申请号：
US16362824
公开号：
US20190224494A1
申请日:
2019.03.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
An apparatus and method for the batch photoactivation of mononuclear cells (MNCs) is described. The system includes a programmable controller configured to automatically separate whole blood in a first collection cycle to obtain a first quantity of MNCs； separate whole blood in a second collection cycle to obtain a second quantity of MNCs while simultaneously photoactivating the first quantity of MNCs to obtain a first quantity of treated MNCs； either store the first quantity of treated MNCs or reinfuse the first quantity of treated MNCs； photoactivate the second quantity of MNCs to obtain a second quantity of treated MNCs； either store the second quantity of treated MNCs or reinfuse the second quantity of treated MNCs； and reinfuse any blood components remaining after the second collection cycle. If the treated MNCs are to be stored, they may optionally be cryopreserved such that the treated MNCs retain their apoptotic properties after cryopreservation and subsequent thawing.
