Use of Mutant Herpes Simplex Virus-2 for Cancer Therapy

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专利权人:

发明人:

Xiaoliu Zhang,Xinping Fu

申请号：

US14602136

公开号：

US20150246086A1

申请日:

2015.01.21

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 comprises a modified/mutated ICP10 polynucleotide encoding a polypeptide having ribonucleotide reductase activity and lacking protein kinase activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/