liquid formulation, use of a formulation, and kit

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专利权人:

GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED

发明人:

George H. Crotts,Sorina Morar-Mitrica

申请号：

BR112015017619

公开号：

BR112015017619A2

申请日:

2014.01.22

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

1/321 1/1 summary "Liquid wool formulation, use of a formulation, and kit" The present invention provides liquid formulations comprising protein-binding proteins. antigens that specifically bind to tnf-alpha. for example, novel anti-TNF antibody variants, such as adalimumab, which exhibit increased fnn receptor binding or increased half-life compared to adalimumab. Also provided are compositions comprising antigen binding proteins and uses of such compositions in the treatment of disorders and disease.1 / 321 1 / 1 resumo “formulaã‡ãƒo lã�quida, uso de uma formulaã‡ãƒo, e, kitâ€� a presente invenã§ã£o fornece formulaã§ãµes lã­quidas que compreendem proteã­nas de ligaã§ã£o de antã­geno que se ligam especificamente ao tnf-alfa. por exemplo, novas variantes de anticorpos anti-tnf, tais como adalimumab, que apresentam ligaã§ã£o aumentada ao receptor de fcrn ou meia-vida aumentada comparada com adalimumab. tambã©m sã£o fornecidas composiã§ãµes compreendendo as proteã­nas de ligaã§ã£o de antã­geno e usos de tais composiã§ãµes no tratamento de distãºrbios e doenã§a.

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中国工程科技知识中心

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