Novel pyrrolopyrimidine compound or salt thereof, pharmaceutical composition containing same, especially agent for prevention and/or treatment of tumors etc based on nae inhibitory effect
The problem to be solved by the present invention is to provide a novel pyrrolopyrimidine compound or a salt thereof having an NAE inhibitory effect as well as a cell growth-suppressing effect. The present invention provides a compound represented by general formula (A) or a salt thereof, and a NAE inhibitor, pharmaceutical composition, and antitumor agent having this compound or a salt thereof as an active ingredient.本發明所欲解決之課題在於提供一種具有NAE抑制作用,且具有細胞增殖抑制效果的新穎吡咯并嘧啶化合物或其鹽。本發明提供一種通式(A)所表示的化合物或其鹽、將該化合物或其鹽作為有效成分之NAE抑制劑、醫藥組成物及抗腫瘤劑。