BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS;BOLAND, THOMAS
发明人:
BOLAND, THOMAS
申请号：
EP13749912
公开号：
EP2814529A4
申请日:
2013.02.13
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
An Inkjet printing method, system, and computer-usable tangible storage device to print cells and biomaterials for three-dimensional cellular scaffolds and engineered skin grafts are disclosed. The process simultaneously deposits living cells, nutrients, growth factors, therapeutic drugs along with biomaterial scaffolds at the right time and location. This technology can also be used for the microvasculature fabrication using appropriate human microvascular endothelial cells and fibrin to form the microvasculature. When printing human microvascular endothelial cells in conjunction with the fibrin, the cells aligned themselves inside the channels and proliferated to form confluent linings. The 3D tubular structure was also found in the printed patterns. Simultaneously printing biological materials to form a three-dimensional cellular scaffold promotes human microvascular endothelial cell proliferation and microvasculature formation.
