PARTICULES DE COMPOSITION PHARMACEUTIQUE, PRÉPARATION À DÉSINTÉGRATION ORALE EN CONTENANT, ET PROCÉDÉ POUR LA PRODUCTION DE PARTICULES DE COMPOSITION PHARMACEUTIQUE
Provided are a pharmaceutical composition particle which is capable of achieving both masking of an unpalatable taste and improvement in dissolution properties, an orally disintegrating tablet containing the pharmaceutical composition particle, and a method for manufacturing a pharmaceutical composition particle. The pharmaceutical composition particle includes a core particle containing a drug and a water-soluble gelling swelling substance； and an outer layer which contains a water-insoluble substance and constitutes a coating provided on the outer side of the core particle. The method for manufacturing a pharmaceutical composition particle according to the present invention includes: a pulverization step of pulverizing a water-soluble gelling swelling substance so that the pulverized water-soluble gelling swelling substance has an average particle diameter of 15 µm or less； a core particle manufacturing step of mixing the water-soluble gelling swelling substance pulverized in the pulverization step and a drug to manufacture a core particle； and an outer layer formation step of coating the core particle with a water-insoluble substance on the outer side of the core particle to form an outer layer.
