シチジン系代謝拮抗剤の高分子誘導体

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专利权人:

日本化薬株式会社

发明人:

増田 亮,恩田 健,真柴 洋子,山本 啓一朗,高塩 一俊

申请号：

JP2007528226

公开号：

JP5000512B2

申请日:

2006.04.27

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

[PROBLEMS] To provide a derivative of a cytidine metabolic antagonist which can exert a high therapeutic effect at a low dose. [MEANS FOR SOLVING PROBLEMS] A polymeric derivative of a cytidine metabolic antagonist which comprises a polymeric compound having a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a cytidine metabolic antagonist, which has such a structure that the carboxyl group in the side chain of the polymeric compound and an amino group in the cytidine metabolic antagonist are bound together to form an amide bond.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/