Joung Han Yim;Se Jong Han;Lee Don Hang;Il Chan Kim;Hari Datta Bhattarai;Su-Geun Yang;Hyoung Seok Lee
发明人:
Joung Han Yim,Il Chan Kim,Se Jong Han,Hyoung Seok Lee,Hari Datta Bhattarai,Su-Geun Yang,Lee Don Hang
申请号：
US14381490
公开号：
US20150031771A1
申请日:
2012.02.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
There is provided a novel use of ramalin for preventing or treating liver diseases, and more specifically, a pharmaceutical composition for preventing or treating hepatic fibrosis or cirrhosis containing ramalin or a pharmaceutically acceptable salt thereof, and a functional food containing the same. It was confirmed that at the time of applying ramalin, which is a compound derived from Ramalina terebrata according to the present invention, to animal models, ramalin may remarkably suppress hepatic fibrosis and lower liver cirrhosis levels as compared to silymarin known as a liver cell protecting ingredient without cytotoxicity to normal liver cells, such that ramalin may be effectively used for preventing or treating hepatic fibrosis and liver cirrhosis.
