FIELD: chemistry.SUBSTANCE: invention relates to novel 4-aminocyclohexane derivatives, having affinity for the µ- opioid receptor and ORL1 receptor. In formulaY1, Y1', Y2, Y2', Y3, Y3', Y4 and Y4' denote -H； Q denotes -R0, -C(O)-R0 or -C(=NH)-R0； R0 and R3 in each case independently denote -C1-8-aliphatic, -aryl, -heteroaryl, -C1-8-aliphatic-C5-cycloaliphatic, -C1-8-aliphatic-aryl； R1 and R2 independently denote unsubstituted -C1-8-aliphatic； -C1-8-aliphatic-C5-cycloaliphatic, -C1-8-aliphatic-aryl； n denotes 0； X denotes -NRa-； Ra denotes unsubstituted -C1-8-aliphatic； Rb denotes unsubstituted -C1-8-aliphatic； "aliphatic" represents a straight saturated hydrocarbon residue which is unsubstituted or mono- or multi-substituted with F atoms； "cycloaliphatic" represents a saturated, unsubstituted monocyclic hydrocarbon residue with 5 carbon atoms in the ring； "aryl" represents phenyl, which can be substituted with -F, -R0 and -OR0； "heteroaryl" represents a 5-member cyclic aromatic moiety containing 1 heteroatom. The heteroatom is N or S, and the heterocyclic ring can be substituted with -F, -R0 and -OR0； the heterocyclic ring can be part of a bicyclic system including phenyl.EFFECT: invention also relates to a drug containing said compounds and use of the compounds to produce a drug for treating pain, stress, epilepsy, learning and memory disorders, drug dependence, cardiovascular diseases, eating disorders and locomotory impairments.9 cl, 10 tbl, 164 exИзобретение относится к новым производным 4-аминоциклогексана, которые обладают сродством к µ-опиоидному рецептору и ORL1-рецептору. В формуле (1) Y1, Y1', Y2, Y2', Y3, Y3', Y4 и Y4' означают -Н； Q означает -R0, -C(=O)-R0 или -C(=NH)-R0； R0 и R3 в каждом случае независимо означает -C1-8-алифат, -арил, -гетероарил, -C1-8-алифат-С5-циклоалифат, -C1-8-алифат-арил； R1 и R2, независимо означают незамещенный -C1-8-алифат； -C1-8-алифат-C5-циклоалифат, -C1-8-алифат-арил； n означает 0； Х означает -NRA-； RA означает незамещенны
