Described is a supporting base (1) for medical instruments (2), comprising a supporting layer (3) having a relative visible front surface (4) and a relative rear surface (5) opposite the visible surface (4) The supporting layer (3) also has a plurality of holes (6) extending from the front surface (4) towards the rear surface (5) More specifically, the supporting layer has a gripping portion (9) positioned on the rear surface (5) and irreversibly joined to the supporting layer (3) to form a single body with said supporting layer (3). The supporting base (1) has at least one opening (17) for inserting, in use, a medical instrument (2), positioned at each hole (6) and extending from the front surface (4) towards the rear surface (5) and through the gripping portion (9).