Apparatus and method for measuring physiological information of a living subject in a vehicle are provided. The apparatus includes an illumination unit configured to emit light at a wavelength and illuminate a region of interest (ROI) of the living subject with the emitted light; a light sensing unit configured to remotely acquire signals of light in a range of wavelengths reflected from the ROI of the living subject responsive to the illumination; a remote photoplethysmography (PPG) extraction unit configured to extract PPG signals from the acquired signals of light; a PPG processing unit configured to process the extracted PPG signals in the form of vital signs and subsequently determine a physical and psychological status of the living subject according to the vital signs; and a control unit configured to activate the illumination unit in a time-varying pattern and to activate the light sensing unit accordingly.