A surgical fastener applier (10) includes a variable drive mechanism (100) disposed within a housing (20) and operably coupled between an input member (110) and an output member (120), the variable drive mechanism being transitionable between at least a first condition, wherein rotation of the input member by a fixed amount effects rotation of the output member a first amount, and a second condition, wherein rotation of the input member by the fixed amount effects rotation of the output member a second amount different from the first amount.
