FALLON, JUSTIN R.,RAFII, MICHAEL,BOWE, MARK,MCKECHNIE, BETH,AMENTA, ALISON,MERCADO, MARY LYNN,HAGIWARA, HIROKI
申请号:
CA2455884
公开号:
CA2455884C
申请日:
2002.08.15
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention provides, among other aspects, compositions and methods fortreating, preventing, and diagnosing diseases or conditions associated with anabnormal level or activity of biglycan; diseases or conditions associated withan abnormal level or activity of collagen VI; disorders associated with anunstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associatedprotein complex (DAPC); and disorders associated with abnormal synapses orneuromuscular junctions, including those resulting from an abnormal MuSKactivation or acetylcholine receptor (AChR) aggregation.