Methods of treating pruritic conditions mediated through histamine H-4 receptors

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专利权人:

Bridge Pharma; Inc.

发明人:

Aberg, A. K. Gunnar,Ciofalo, Vincent B.

申请号：

AU2014304983

公开号：

AU2014304983A1

申请日:

2014.07.31

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The methods disclosed herein relate to the treatment of histamine H-4 - related dermal disorders, by administering a histamine H-4 receptor inverse agonist that selectively accumulates at the biophases for the disorders, specifically RS-norketotifen or a pharmaceutically acceptable salt thereof. Potentiated antipruritic activity by simultaneous inhibition of histamine H-1 receptors and histamine H-4 receptors are described.

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中国工程科技知识中心

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http://www.ckcest.cn/home/