Paul Nioi,Peter Coward,Christopher Murawsky,Derek E. Piper,Fernando Garces,Jun Zhang,Yang Li,Brian Mingtung Chan
申请号：
US16230356
公开号：
US20190248902A1
申请日:
2018.12.21
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Antigen binding proteins that interact with ASGR, ASGR-1 and/or ASGR-2 are described as well as methods of making and using such antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of ASGR, ASGR-1 and/or ASGR-2 antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of interfering RNA compositions that reduce expression of ASGR, ASGR-1 and/or ASGR-2 are described.
