NIOI, PAUL,COWARD, PETER,MURAWSKY, CHRISTOPHER,PIPER, DEREK E.,GARCES, FERNANDO,ZHANG, JUN,LI, YANG
申请号:
TW105131432
公开号:
TW201726726A
申请日:
2016.09.29
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
Antigen binding proteins that interact with ASGR, ASGR-1 and/or ASGR-2 are described as well as methods of making and using such antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of ASGR, ASGR-1 and/or ASGR-2 antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of interfering RNA compositions that reduce expression of ASGR, ASGR-1 and/or ASGR-2 are described.