PROBLEM TO BE SOLVED: To provide a shellfish floating larva breeding method using lysozyme in which shellfish floating larvae are made to orally take in the lysozyme to promote extinction activities of digestive tract epithelial cells and surrounding tissues, and thereby the uptake of lymphotoxin to the digestive tract epithelial cells and its effect are reduced and the occurrence of failure of digestive tract epithelial cells is prevented, and as a result, a survival rate can be improved while maintaining the growth of the shellfish floating larvae.SOLUTION: A shellfish floating larva breeding method using lysozymes is characterized in that lysozyme is orally supplied to shellfish floating larvae as lysozyme hydrochloride to prevent the occurrence of failure of digestive tract epithelial cells, and thereby a survival rate is improved while maintaining the growth.