An e-liquid pumping assembly for supplying e-liquid to an atomizer includes a housing, an e-liquid bottle, and a pumping head assembly. The pumping head assembly includes a piston, a pumping body clamped with the e-liquid bottle by a first sealing portion, a pumping cover clamped with the pumping body, a feeding tube connected to the atomizer and the pumping body. The piston includes a first lower end inserted into the pumping body and a first upper end exposed from the pumping cover. The e-liquid suction pipe includes a second lower and upper ends respectively inserted into the e-liquid bottle and the pumping body. The piston is pressed to expel air from the pumping body so that e-liquid enters the pumping body through the e-liquid suction pipe. The piston is again pressed for pushing the e-liquid out of die pumping body to the atomizer through the feeding tube.
