The present invention is directed to a coating composition, particularly an architectural coating composition, comprising antimicrobial agents based on zinc pyrithione and zinc oxide, a process for the manufacture of such coating compositions, and their use. Coating compositions comprising zinc pyrithione and zinc oxide as antimicrobial agents exhibit antiviral, antibacterial and/or antifungal activities and efficacies, rendering them suitable for creating hygienic surfaces. The antimicrobial efficacy of these coating compositions will have applications in areas where microbial transmission and infection potential are high. More specifically, the coating compositions comprising zinc pyrithione and zinc oxide exhibit a synergistic antiviral efficacy against the Coxsackievirus type A16 and Enterovirus type 71, viruses responsible for the transmission and infection of hand-foot-mouth disease in children. Additional antiviral or antimicrobial agents that can be used in the coating compositions of the invention include silver in the form of organic or inorganic silver salts.本發明係針對一種包含基於吡啶硫酮鋅及氧化鋅之抗微生物劑的塗覆組成物,尤其建築塗覆組成物,一種製造該等塗覆組成物之方法及該等塗覆組成物之用途。包含作為抗微生物劑之吡啶硫酮鋅及氧化鋅的塗覆組成物展示抗病毒、抗細菌及/或抗真菌活性及功效,使其適合於產生衛生表面。此等塗覆組成物之抗微生物功效將應用於其中微生物傳播及感染可能性較高之領域中。更特定言之,包含吡啶硫酮鋅及氧化鋅之該等塗覆組成物展示針對A16型柯薩奇病毒(Coxsackievirus Type A16)及71型腸道病毒(Enterovirus Type 71)之協同抗病毒功效,該等病毒為造成兒童中手足口病之傳播及感染的病毒。可用於本發明之塗覆組成物中的額外抗病毒或抗微生物劑包括呈有機或無機銀鹽形式之銀。
