The present invention discloses calculi breakup method and apparatus. The method comprises: inserting a combination of an endoscope with a driving assembly and a milling assembly, or a combination of an endoscope and a sleeve with a driving assembly and a milling assembly into the urinary intracavity starting up a driving unit to drive the milling assembly so as to mill the calculi in the intracavity into powder and, discharging the milled calculi powder out of the body. Compared to the other calculi breakup method, the calculi breakup apparatus according to the present invention has the advantages of high calculi breakup speed, high efficiency, no heat during the calculi breakup, no hurt to the urinary mucous membrane, painless, short time for the treatment, low calculi residual rate, simple operation, and easy maintenance.
