The present invention relates to a device for detecting a health condition of a subject (15), comprising a data interface (12) for receiving sensor data (14) of said subject (15) and one or more disease classification parameters (16) for characterizing one or more diseases, a user interface (18) for receiving a user input (20) related to a disease activity, an analysis unit (26) for extracting one or more physiological and/or behavioral features from said received sensor data (14), an optimizer unit (28) for optimizing said one or more disease classification parameters (16) based on a correlation analysis between said one or more physiological and/or behavioral features and said user input (20), and a detection unit (30) for detecting a health condition of said subject (15) by applying said one or more disease classification parameters (16) to said one or more physiological and/or behavioral features.