LEE, KWANGHO,NIU, DEQIANG,PETTER, RUSSELL C.,BAEVSKY, MATTHEW FRANK,SINGH, JUSWINDER
申请号：
CA2815858
公开号：
CA2815858C
申请日:
2011.10.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity are disclosed. Selectivity in inhibition of various mutant-EGFR is disclosed. Pharmaceutical compositions containing the pyrimidine derivatives, and methods of treating diseases associated with EGFR kinase activity comprising administration of the pyrimidine derivatives or pharmaceutical compositions containing the pyrimidine derivative, are described.
