HETEROCYCLIC COMPOUNDS AND USES THEREOF

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专利权人:

CELGENE AVILOMICS RESEARCH; INC.

发明人:

LEE, KWANGHO,NIU, DEQIANG,PETTER, RUSSELL, C.,BAEVSKY, MATTHEW, FRANK,SINGH, JUSWINDER

申请号：

SG2013033857

公开号：

SG190116A1

申请日:

2011.10.31

申请国别(地区):

SG

年份:

2013

代理人:

摘要：

Heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity are disclosed. Selectivity in inhibition of various mutant-EGFR is disclosed. Pharmaceutical compositions containing the pyrimidine derivatives, and methods of treating diseases associated with EGFR kinase activity comprising administration of the pyrimidine derivatives or pharmaceutical compositions containing the pyrimidine derivative, are described.

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