BARBARA JANE BADENOCH-JONES;PAUL RONALD PLANTE;SEBASTIAN MARIO MARCUCCIO
发明人:
PAUL RONALD PLANTE,SEBASTIAN MARIO MARCUCCIO,BARBARA JANE BADENOCH-JONES
申请号：
US14036442
公开号：
US20140186306A1
申请日:
2013.09.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to novel AMPK agonist containing compositions that are adapted for localised use in treating inflammation and/or pain due to disease or injury in a human or animal. The novel compositions of the invention are useful in the treatment of a variety of conditions including osteoarthritis (OA), synovitis, tendonitis, desmitis； cystitis, osteitis and laminitis. Routes of administration include intra-articular, direct injection into tissues, instillation, retrograde perfusion and topical. AMPK agonists which can be used include AICAR, metformin, phenformin, A-769662, resveratrol, berberine and polyphenols.
