NEW ASSOCIATION BETWEEN 4-{3-[CIS-HEXAHYDROCYCLOPENTA[C]PYRROL-2 (1H) -YL]PROPOXY??BENZAMIDE AND AN ACETYLCHOLINESTERASE INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
The present invention is a pharmaceutical, a derivative of 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy}benzamide of chemical formula (I) or an additional salt with a pharmaceutically active acid or base, and an acetylcholinesterase inhibitor. [Reference numerals] (AA) Test procedure; (BB) Tronche et al. changed after 2010; (CC) Food; (DD) No food; (EE) Contextual; (FF) Serial distinguishment test; (GG) Two different contexts of two continuous distinguishment; (HH,SS) Treatment; (II,TT) Room C; (JJ,UU) Injection of a compound or glycone; (KK) Learn; (LL,OO,WW) Room A; (MM,PP) hole with a bait; (NN) Room B; (QQ) Retention time; (RR) Animal quarters; (VV) Test; (XX) Correct response; (YY) Mistake; (ZZ) Interference response본 발명은 하기 화학식(I)의 4-{3-[시스-헥사하이드로시클로펜타[c]피롤-2(1H)-일]프로폭시}벤즈아미드 또는 약제학적으로 허용되는 산 또는 염기와의 이의 부가염과 아세틸콜린에스테라제 억제제의 회합체 및 의약에 관한 것이다: