Oral and injectable formulations of the tetracycline compound 9-[(2,2-dimethyl-propylamino)-methyl]-minocycline

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专利权人:

PARATEK PHARMACEUTICALS; INC.

发明人:

JOHNSTON, SEAN

申请号：

NZ58842809

公开号：

NZ588428A

申请日:

2009.03.30

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

The disclosure relates to an oral formulation in tablet form, comprising 9-[(2,2-dimethyl-propyl amino)methyl]-minocycline (a tetracycline compound) or a salt thereof, a diluent, a stabilizer, a glidant, a lubricant, and a disintegrant； and an injectable formulation comprising 90-110 mg of 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline free base or a salt thereof, one or more components selected from a lyoprotectant, an anti-oxidant, and a pH adjustment compound, and a pharmaceutically acceptable carrier.

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