The present invention is a hand-held endoscopic device with a rotation control, having a mainframe, a flexible cable, and a tube module. Moreover, the tube module includes a probe, a image capturing element and a sheath besides, the second front end of the sheath has an opening which includes a mirror to allow the user to rotate the opening of the sheath in accordance with the situation, so that the image capturing element can reflect the light through the mirror to capture the image from different perspectives.