STARKE INGEMAR,INGEMAR STARKE,DAHLSTROM MIKAEL ULF JOHAN,MIKAEL ULF JOHAN DAHLSTROM,BLOMBERG DAVID,DAVID BLOMBERG,ALENFALK SUZANNE,SUZANNE ALENFALK,SKJARET TORE,TORE SKJARET,LEMURELL MALIN,MALIN LEMUR,MALIN LEMURELL,LEMURELL MA
申请号:
PL369078
公开号:
PL216023B1
申请日:
2002.09.05
申请国别(地区):
PL
年份:
2014
代理人:
摘要:
The present invention relates to compounds of formula (I) wherein R<;SUP>;v<;/SUP>;, R<;SUP>;1<;/SUP>;, R<;SUP>;2<;/SUP>;, R<;SUP>;x<;/SUP>;, R<;SUP>;y<;/SUP>;, M, R<;SUP>;z<;/SUP>;, v, R<;SUP>;3<;/SUP>;, R<;SUP>;4<;/SUP>;, R<;SUP>;5 <;/SUP>;and R<;SUP>;6 <;/SUP>;are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.