United States of America, as represented by the Secretary, Department of Health and Human Services C/O National Institutes of Health, Office of Technology Transfer;United States of America; Office of Technology Transfer; Department of Health and Human Services C/O National Institutes of Health; as represented by the Secretary;Research Triangle Institute
发明人:
Blough, Bruce E.,Rothman, Richard,Landavazo, Antonio,Page, Kevin M.,Decker, Ann Marie
申请号：
AU2011255276
公开号：
AU2011255276A1
申请日:
2011.05.20
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Provided herein are compounds and prodrugs and methods of preparation of compounds and prodrugs that are capable of functioning as releasers and/or uptake inhibitors of one or more monoamine neurotransmitters, including dopamine, serotonin, and norepinephrine. Also provided are pharmaceutical compositions comprising one or more of these compounds or prodrugs, which may further comprise one or more additional therapeutic agents. Also provided are methods of treatment of various conditions that may be responsive to modification of monoamine neutrotransmitter levels, such as pre-obesity, obesity, addiction, and depression.
