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NITROGENIC ANALOGUES OF SALINOMYCINE, SYNTHESIS AND USE AGAINST CANCER STAM CELLS AND MALARIA
专利权人:
Centre National de la Recherche Scientifique (CNRS);Institut National de la Santé et de la Recherche Médicale (INSERM);Université Paris Descartes
发明人:
MEHRPOUR, Maryam,RODRIGUEZ, Raphael,HIENZSCH, Antje,TRANG, Mai,HAMAI, Ahmed
申请号:
DK15766107
公开号:
DK3191493T3
申请日:
2015.09.14
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention concerns compounds of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diasteroisomers thereof formual (I): wherein at least one of W, X and Y is selected from the group consisting of -NR1R2; - NR3-(CH2)n-NR4R5; -O-(CH2)n-NR4R5; -NR3-(CH2)n-N+R6R7R8; and -O-(CH2)n-N+R6R7R8 and Z is a functional group capable of chelating iron salts. The present invention also concerns the compounds of formula (I) for use as a drug, in particular, in the treatment of cancer and malaria.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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