MADERNA, Andreas,SUBRAMANYAM, Chakrapani,TUMEY, Lawrence N.,CHEN, Zecheng,CASAVANT, Jeffrey M.
申请号:
SG11201706991Y
公开号:
SG11201706991YA
申请日:
2016.03.15
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
where F1, L1, T, L2 and F2 are as defined herein, useful for the treatment for proliferative diseases, where the inventive dimers can function as stand-alone drugs, payloads in antibody-drug-conjugates (ADCs), and linker-payload compounds useful in connection with the production or administration of such ADCs and to compositions including the aforementioned dimers, linker-payloads and ADCs, and methods for using these dimers, linker-payloads and ADCs, to treat pathological conditions including cancer.