The Board of Regents for Oklahoma State University
发明人:
Antonius G. P. Oomens
申请号:
US16257738
公开号:
US10799576B2
申请日:
2019.01.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Recombinant, live, attenuated viruses of the Pneumoviridae family are disclosed that include a baculovirus GP64 envelope glycoprotein or variant or fragment thereof and a respiratory syncytial virus (RSV) F protein variant or fragment thereof. Also disclosed are polynucleotides encoding the virus as well as pharmaceutical compositions and vaccines containing the virus. In addition, methods of producing and using each of the above compositions are also disclosed.