BRASEL, KENNETH, ALLAN,FOSTER, STEPHEN,CERRETTI, DOUGLAS, PAT,SUN, JILIN,SMOTHERS, JAMES, F.,MEHLIN, CHRISTOPHER
申请号:
RSP20171242
公开号:
RS56743B1
申请日:
2008.08.19
申请国别(地区):
RS
年份:
2018
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-I, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.