An electrical stimulation system to provide pulse stimulation to an area of a living body by way of one or more electrode leads applied to the area, the area including an associated resistance element and an associated capacitance element. The system may include a pulse generating circuit having a controllable output voltage to generate constant voltage pulses to the one or more electrode leads, wherein the corresponding current signal of each constant voltage pulse includes an exponential decay to a steady state current value. The system may include a controller configured to estimate the associated resistance element of the area, determine a specified target steady state current value to be applied to the area, and control the pulse generating circuit to generate a constant voltage pulse to the one or more electrode leads at a calculated voltage level which achieves the specified target steady state current value to the area.