ARMER, RICHARD EDWARD,PETTIPHER, ERIC ROY,WHITTAKER, MARK,WYNNE, GRAHAM MICHAEL,VILE, JULIA,SCHROER, FRANK
申请号：
CA2712017
公开号：
CA2712017C
申请日:
2009.01.19
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds of general formula (I) wherein W is chloro or fluoro； R1 is phenyloptionally substituted with one or moresubstituents selected from halo, -CN, -C1-C6 alkyl, -SOR3, -SO2R3, -SO2N(R2)2,-N(R2)2, -NR2C(O)R3, -CO2R2, - CONR2R3, -NO2,-OR2, -SR2, -O(CH2)p OR2, and -O(CH2)p O(CH2)q OR2 wherein each R2 isindependently hydrogen, -C1-C6 alkyl, -C3-C8 cycloalkyl,aryl or heteroaryl； each R3 is independently, -C1-C6 alkyl, -C3-C8 cycloalkyl,aryl or heteroaryl； p and q are each independently aninteger from 1 to 3； and their pharmaceutically acceptable salts, hydrates,solvates, complexes or prodrugs are useful in orallyadministrable compositions for the treatment of allergic diseases such asasthma, allergic rhinitis and atopic dermatitis.
