A handpiece for an intense pulsed light therapy device comprises: - a base (2)； - an optical unit (3) to be attached to the base (2), the optical unit (3) defining a housing for a flash lamp cartridge (70) with a fluid connector (200) and an electrical connector (150), the optical unit (3) being designed to apply the fluid connector (200) of the cartridge, at the end of a pivoting movement, to a corresponding connector (210) provided on the base, in order to establish a circulation of cooling fluid between the cartridge and the base.
