Modified proteases that inhibit complement activation

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专利权人:

カタリスト・バイオサイエンシーズ・インコーポレイテッド

发明人:

エドウィン・エル・マディソン,ジャック・ヌグイェン,サンドラ・ウォー・ラグルズ,クリストファー・ディ・サノス

申请号：

JP2012223555

公开号：

JP5860789B2

申请日:

2012.10.05

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

Provided are methods for and compounds for modulating the complement system. In particular, compounds are provided that inhibit complement activation and compounds are provided that promote complement activation. The compounds are therapeutics by virtue of their effects on the complement system. Hence, the compounds that inhibit complement activation can be used for treatment of ischemic and reperfusion disorders, including myocardial infarction and stroke, sepsis, autoimmune diseases, inflammatory diseases and diseases with an inflammatory component, including Alzheimer's Disease and other neurodegenerative disorder.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/