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DÉRIVÉ À CYCLE CONDENSÉ À 9 CHAÎNONS
专利权人:
Ltd.;Shionogi & Co.
发明人:
OHYABU, Naoki,KURAHASHI, Kana,NISHIURA, Yuji,KATOU, Manabu,MIYAZAKI, Keisuke,SASAKI, Yoshikazu,WADA, Toshihiro,IWATSU, Masafumi
申请号:
EP16772963
公开号:
EP3279187A4
申请日:
2016.03.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The purpose of the present invention is to provide novel compounds having ACC2 selective inhibitory activity. In addition, the present invention provides a pharmaceutical composition comprising the compound. A compound of Formula: or its pharmaceutically acceptable salt, wherein, R 1 is substituted or unsubstituted fused aromatic heterocyclyl represented by Formula: wherein, ring B is 5-membered ring, ring C is 6-membered ring; ring A is substituted or unsubstituted non-aromatic carbocycle or the like; -L 1 - is -O-(CR 6 R 7 )m- or the like; -L 2 - is -O-(CR 6 R 7 )n- or the like; each R 6 is independently hydrogen or the like; each R 7 is independently hydrogen or the like; each m is independently an integer of 0, 1, 2 or 3; each n is independently an integer of 1, 2 or 3; R 2 is substituted or unsubstituted alkyl; R 3 is hydrogen or substituted or unsubstituted alkyl; R 4 is substituted or unsubstituted alkylcarbonyl or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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