An orthopedic surgical instrument set is disclosed herein. The instrument set includes (i) at least one tamp, the tamp including a substantially cylindrical body portion (ii) at least one trephine, the trephine having a first end and a second end, the second end of the trephine having a plurality of teeth disposed thereon, the trephine being provided with a cylindrical passageway disposed therethrough for receiving the substantially cylindrical body portion of the tamp and (iii) a guide stand having a base portion and an upper portion disposed above the base portion, the upper portion of the guide stand being provided with a guide aperture disposed therein for receiving the at least one trephine. A method of fabricating a bone plug, which utilizes the orthopedic surgical instrument set, is also disclosed herein.