Embodiments of the present invention provide a headphone and an interaction system. The headphone includes: a controller electrically connected to the Type-C interface, a biological features detection module connected to the controller, a microphone electrically connected to the controller, and a loudspeaker electrically connected to the controller. The biological features detection module is configured to detect biological features of a user wearing the headphone; and the controller is configured to control paring between the Type-C interface and a terminal and communication between the terminal and the biological features detection module, the microphone and the loudspeaker when the headphone is in a digital mode, to control detection of biological features and processing of audio data.