1. Manufacture and methods of pyridine compounds, ultrapure compounds and their salts for the treatment of diseases and diseases of H4 (H4) tissue receptor
It refers to compounds containing N4 - (cyclopropylmethyl) - 6 - [(3R) - 3 - (methylamine) pirrolidin-1-il) pirimidin-2, 4-butyl-6 - [(3 - (methylamine) pirrolidin-1-il) pirimidin-2, 4-diamin Tartra, less than 1% [(3 - (methylamine) pirrolidin-1-il] pirimidin-2, 4-diamin and less than 0.26% impurities. These ingredients are used to treat inflammation controlled by H4 tissue receptors, such as skin diseases, asthma, urticaria, diabetes mellitus nefropatia, etc.Se refiere a composiciones que comprenden dihidrato de N4-(ciclopropilmetil)-6-[(3R)-3-(metilamino)pirrolidin-1-il]pirimidin-2,4-diamina tartrato, menos del 1% de 4-N-butil-6-[(3-(metilamino)pirrolidin-1-il]pirimidin-2,4-diamina y menos del 0,26% de impurezas. Dichas composiciones se emplean en el tratamiento de enfermedades inflamatorias mediadas por el receptor histaminico H4, como dermatitis atopica, asma, urticaria, nefropatia diabetica, entre otras.
