ZABARYLO Urszula (DE),ЗАБАРЫЛО Урсзула (DE),MINET Olaf (DE),МИНЕТ Олаф (DE),Artyushenko Vyacheslav Grigorevich (RU),АРТЮШЕНКО Вячеслав Григорьевич (RU),Tuchina Darya Kirillovna (RU),ТУЧИНА Дарья Кирил
申请号：
RU2018126357
公开号：
RU0002697594C1
申请日:
2018.07.17
申请国别(地区):
RU
年份:
2019
代理人:
摘要：
FIELD: medicine.SUBSTANCE: group of inventions refers to medicine, namely to a method of biomedical imaging and a device for its implementation, in particular optical imaging of images, and can be used for non-invasive diagnosis of diseases of joints, including rheumatoid arthritis. Method of obtaining an optical image of interphalangeal joints involves exposing a finger joint to a biocompatible immersion agent having hyperosmotic action and a refraction index equal to or greater than the average skin refraction index, radiographing of the joint with optical radiation successively at wavelengths lying in the area of the biological tissue transparency window, recording corresponding images with the help of a digital camera located on the other side of the light source relative to the position of the joint, determining image contrast is carried out within first-order statistics, wherein before illumination, the region to be examined is immersed into an immersion agent for 8–10 minutes until skin tension is achieved, wherein immersion agent is placed in vessel with two flat walls located opposite each other, through which there is a radiographic examination. Optical sensor for recording the image of interphalangeal joints for implementing method of 1 comprises one laser light source, equipped with a light guide, a digital monochrome camera, a programmable control unit, wherein laser radiation source and digital monochrome camera are installed in body-support for hand, in which there is a window and an additional hole made opposite applicator chamber to accommodate finger, installed with possibility of movement, made of transparent glass or plastic, filled with immersion agent and having two flat and two rounded walls, one end of the light guide is fixed by a connector opposite flat walls of the applicator chamber, and the other end is fixed on the body-support for the hand by means of a hinge joint with possibility of turning through 90°, wherein digital camera is inst
