Daniel J. Wendt,Shinong Long,Sianna Castillo,Christopher P. Price,Mika Aoyagi-Scharber,Michel Claude Vellard,Augustus O. Okhamafe
申请号：
US14660488
公开号：
US20160256553A1
申请日:
2015.03.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).
